1 Bromo 3 Chloro Propane

1 Bromo 3 Chloro Propane Specification

CAS No
109-70-6

Application
Pharmaceutical

Properties
It is a clear and colorless liquid that is soluble in ethanol, ether, and chloroform but insoluble in water.

Purity
99 %

Shape
Irregular

Product Type
LIQUID

Density
1.592 g/mL at 25 C (lit.) Gram per litre (g/L)

Appearance
CLEAR LIQUID

Refractive Rate
n20/D 1.486(lit.)

Solubility
VOLATILE

Smell
Other

Melting Point
144-145 C (lit.)

Physical Form
Liquid

Taste
Other

Storage
Room Temperature

Usage
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

Molecular Formula
C3H6BrCl

Molecular Weight
157.44 Grams (g)

Poisonous
NO

1 Bromo 3 Chloro Propane Trade Information

Minimum Order Quantity
25 Kilograms

Sample Available
Yes

Sample Policy
Contact us for information regarding our sample policy

Packaging Details
25 KG PACK

Main Export Market(s)
Asia

Main Domestic Market
All India

About 1 Bromo 3 Chloro Propane

1-Bromo-3-chloropropane is an organohalogen compound with the formula Br(CH)Cl. It is a colorless liquid, produced by free-radical addition of hydrogen bromide to allyl chloride. It is used as an alkylating agent to install the (CH)Cl and (CH) groups. For example, it is a precursor to 4-chlorobutyronitrile.

Versatile Pharmaceutical Intermediate

1-Bromo-3-chloropropane is a valuable intermediate in the synthesis of active pharmaceutical ingredients such as gemfibrozil and reproterol. Its reliable purity and solubility profile make it ideal for producing materials used in cardiovascular and analgesic drugs. The compounds versatility extends to its role in creating crucial APIs for diverse therapeutic needs.

Innovative Solution for RNA Isolation

This compound is utilized as an efficient phase separation reagent for isolating high-quality ribonucleic acid (RNA). It serves as a replacement for chloroform in nucleic acid separations, offering improved safety and effectiveness. Laboratories and research institutions benefit significantly from its ability to facilitate cleaner and more reliable RNA extraction processes.

FAQs of 1 Bromo 3 Chloro Propane:

Q: How is 1-Bromo-3-chloropropane typically stored for preservation?

A: 1-Bromo-3-chloropropane should be stored at room temperature to maintain its stability. Avoid exposure to moisture and extreme temperatures to preserve its purity and physical properties.

Q: What are common uses of 1-Bromo-3-chloropropane in pharmaceutical applications?

A: It is primarily employed as an intermediate in the synthesis of APIs for drugs treating cardiovascular diseases and providing analgesic effects. Additionally, it is used in the preparation of compounds like gemfibrozil and reproterol.

Q: Where can 1-Bromo-3-chloropropane be purchased or sourced?

A: This compound is available through exporters, manufacturers, suppliers, and traders in India. It is distributed primarily for industrial and research use.

Q: What benefit does 1-Bromo-3-chloropropane offer in nucleic acid separations?

A: It provides a safer alternative to chloroform for RNA isolation, facilitating efficient phase separation during nucleic acid extraction while improving the quality of the isolated RNA.

Q: Is 1-Bromo-3-chloropropane considered poisonous, and what precautions should be taken?

A: No, it is not classified as poisonous, but standard chemical safety protocols should be observed, including the use of gloves and protective eyewear during handling to prevent accidental exposure.

Q: Can 1-Bromo-3-chloropropane dissolve in water?

A: No, this compound is insoluble in water but is easily soluble in organic solvents such as ethanol, ether, and chloroform.

Q: How is 1-Bromo-3-chloropropane used in laboratory processes?

A: In addition to pharmaceutical synthesis, it acts as a phase separation reagent for high-quality RNA isolation, making it a critical component in molecular biology laboratories.

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